SCI07021 2019 Pharmaceutical Pre-Formulation Studies

This module aims to provide the student with an understanding of the techniques employed in the early phase of research & development, in which pre-formulation studies focus on assessing the physical and chemical properties of a drug molecule that affect the molecules performance and activity. This provides important information for formulation design or supports the need for molecular modification prior to the compounding process that will assist in developing a stable, safe and effective formulation with maximum bioavailability.

Pharmaceutics is one of the most diverse subject areas in all of pharmaceutical science. In brief, it is concerned with the scientific and technological aspects of the design and manufacture of dosage forms or medicines. An understanding of pharmaceutics is therefore vital for all pharmacists and those pharmaceutical scientists who are involved with converting a drug or a potential drug into a medicine that can be delivered safely, effectively and conveniently to the patient. Now in its fourth edition, this best-selling textbook in pharmaceutics has been brought completely up to date to reflect the rapid advances in delivery methodologies by eye and injection, advances in drug formulations and delivery methods for special groups (such as children and the elderly), nanomedicine, and pharmacognosy. At the same time the editors have striven to maintain the accessibility of the text for students of pharmacy, preserving the balance between being a suitably pitched introductory text and a clear reflection of the state of the art. provides a logical, comprehensive account of drug design and manufacture includes the science of formulation and drug delivery designed and written for newcomers to the design of dosage forms New to this edition New editor: Kevin Taylor, Professor of Clinical Pharmaceutics, School of Pharmacy, University of London. Twenty-two new contributors. Six new chapters covering parenteral and ocular delivery; design and administration of medicines for the children and elderly; the latest in plant medicines; nanotechnology and nanomedicines, and the delivery of biopharmaceuticals. Thoroughly revised and updated throughout.

Succeed in your course with Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems, the most comprehensive source on this subject available today!

Essentials of Pharmaceutical Preformulation: A study guide for students and researchers in pharmacy and pharmaceutical sciences describes basic principles of pharmaceutical preformulation for undergraduate level pharmacy students and newly employed workers in the pharmaceutical field who do not have a pharmaceutical background. Successful preformulation requires knowledge of a number of concepts (solubility, partition coefficient, acid dissociation), familiarity with a range of analytical techniques and their application to dosage form design. This text takes these concepts and explains them in the context of pharmaceutical development .Special focus is given to the principles and use of analytical apparatus, providing a core set of transferable knowledge skills. The material is presented in the order that would be followed when developing a medicine and maps onto the indicative syllabus of pharmacy from the Royal Pharmaceutical Society It is divided into three sections: Basic concepts, Solid-state properties and Macroscopic properties and includes easy to follow text highlighted with relevant pharmaceutical examples

Colloidal systems are important across a range of industries, such as the food, pharmaceutical, agrochemical, cosmetics, polymer, paint and oil industries, and form the basis of a wide range of products (eg cosmetics & toiletries, processed foodstuffs and photographic film). A detailed understanding of their formation, control and application is required in those industries, yet many new graduate or postgraduate chemists or chemical engineers have little or no direct experience of colloids. Based on lectures given at the highly successful Bristol Colloid Centre Spring School, Colloid Science: Principles, Methods and Applications provides a thorough introduction to colloid science for industrial chemists, technologists and engineers. Lectures are collated and presented in a coherent and logical text on practical colloid science.

The Handbook of Pharmaceutical Excipients contains essential data on the physical properties of excipients, their safe use and potential toxicity.

Pharmaceutical Preformulation and Formulation: A Practical Guide from Candidate Drug Selection to Commercial Dosage Form reflects the mounting pressure on pharmaceutical companies to accelerate the new drug development and launch process, as well as the shift from developing small molecules to the growth of biopharmaceuticals. The book meets the need for advanced information for drug preformulation and formulation and addresses the current trends in the continually evolving pharmaceutical industry. Topics include: Candidate drug selection Drug discovery and development Preformulation predictions and drug selections Product design to commercial dosage form Biopharmaceutical support in formulation Development The book is ideal for practitioners working in the pharmaceutical arenaincluding R&D scientists, technicians, and managersas well as for undergraduate and postgraduate courses in industrial pharmacy and pharmaceutical technology.

N/A

The International Journal of Pharmaceutics - (Elsevier publishers Ltd)

http://sciencedirect.com/science/journal/03785173

None

None