PHAR08003 2023 Advanced Medical Pharmacology
Full Title
Advanced Medical Pharmacology
Transcript Title
AdvMedPharm
Code
PHAR08003
Attendance
100 %
Subject Area
PHAR - 0512 Pharmacology/Pharma Scie
Department
HEAL - Health & Nutritional Sciences
Level
08 - Level 8
Credit
05 - 05 Credits
Duration
Semester
Fee
€
Start Term
2023 - Full Academic Year 2023-24
End Term
9999 - The End of Time
Author(s)
Thomas Smyth, Paul Nolan, Mary Garvey
Programme Membership
SG_SCLIN_H08 202300 Bachelor of Science (Honours) in Clinical Measurement Physiology
Description
This module introduces the fundamental principles of pharmacology (pharmacokinetics, pharmacodynamics) for clinical measurement science. Essential key concepts of pharmacodynamics, pharmacokinetics, bioavailability, metabolism, elimination and drug design will be studied. Toxicology and target organ toxicity including the liver, GIT, nervous system, endocrine and cardiovascular disease and treatment will be studied.
Learning Outcomes
On completion of this module the learner will/should be able to;
1.
Explain key pharmacology concepts including pharmacodynamics and pharmacokinetics
2.
Examine the clinical application of therapeutics including anti-inflammatories, analgesics, opioids, anti depressants etc
3.
Outline toxicology, drug toxicity, development and dose response relationships and concepts in a practical manner.
4.
Analyse and describe the physiological interaction between drug therapy for a range of diseases and key organs including the GIT, liver, nervous system, endocrine, cardiovascular system.
5.
Apply an understanding of drug receptor binding, therapeutic mode of action, drug tolerance and addiction
Teaching and Learning Strategies
This module will consist of online delivery of 1 hours per week including some interactive discussion lectures. Independent learning hours 4 hrs/week will be needed. Active learning will be incorporated in to this module.
A variety of methods of instruction such as discussion, group work, interactive exercises, use of online resources and/or use of audio/visual material will be provided. Core skills will be embedded into all modules to ensure all students have an equal opportunity to succeed. This may include academic writing, oral presentations, reading techniques or research abilities.
Lecture will provide tutorials to students on topics and academic writing tutorials where needed.
Module Assessment Strategies
The pass mark for this module will be 50%.
100% Continuous assessment module with CA ongoing throughout the semester.
CA will include the following:
- Case Studies with analysis
- Long Answer Questions (LAQs)
Repeat Assessments
Repeat CA will be issued for students needing repeat assessment.
This module contains 'must pass' assessments. The minimum ‘pass’ mark for this module overall is 50%, in addition to meeting the minimum attendance requirement.
Indicative Syllabus
- This module will introduce students to the scientific field of pharmacology where students will gain an understanding of the key concepts of pharmacodynamics and pharmacokinetics.
- The module is designed to provide a good understanding of the theoretical concepts of pharmacology and will include drug classification, mode of action, clinical side effects, drug dependance, addiction and modes of drug delivery with particular focus on clinical science.
- The module will provide students with an understanding of the interaction of drug molecules with bodily cells and organs with therapeutic effect, side effects and drug dependence discussed.
- Toxicology factors relating to drug therapy will be a key components including LC50, therapeutic index etc.
- This module provides detailed understanding of pharmacology in relation to organ systems linked to GI, Vascular, Neurology, Respiratory and Cardiovascular physiology
- Understanding the systems and the interactions between the systems is the initial step in learning how a drug affects the body.
- This module will also describe how a drug's impact occurs when it comes in contact with a chemical component of the body e.g. enzymes, hormones, membranes etc.
- Key therapeutic agents such as analgesics (non steroidal anti-inflammatories, opioids), anti depressants (SSRI, NSRI, DRI, TCA).
- Therapeutics specific to the five disciplines of clinical measurement physiology (GI, Vascular, Neurology, Respiratory and Cardiovascular physiology) will be outlined.
- Applied pharmacology for clinical specialists including drug therapy such as antimicrobials, chemotherapeutics, anaesthetics, analgesics, opioids, anti depressants amongst others will be studied.
- Important factors such as dose response, ED50, LC50, receptor binding (partial, agonists, antagonist) are to be incorporated demonstrating key clinical concepts.
- Clinical application of therapeutics for a range body systems.
Coursework & Assessment Breakdown
Coursework & Continuous Assessment
100 %
Coursework Assessment
| Title | Type | Form | Percent | Week | Learning Outcomes Assessed | |
|---|---|---|---|---|---|---|
| 1 | LAQ | Coursework Assessment | Assessment | 20 % | Week 4 | 1 |
| 2 | Case study | Coursework Assessment | Assignment | 25 % | Week 7 | 1,2 |
| 3 | LAQ | Coursework Assessment | Assessment | 25 % | Week 10 | 3,4 |
| 4 | LAQ | Coursework Assessment | Assessment | 30 % | Week 13 | 3,4,5 |
Full Time Mode Workload
| Type | Location | Description | Hours | Frequency | Avg Workload |
|---|---|---|---|---|---|
| Lecture | Lecture Theatre | Lecture | 1 | Weekly | 1.00 |
| Independent Learning | Flat Classroom | Independent Learning | 5 | Weekly | 5.00 |
| Directed Learning | Not Specified | directed learning | 1 | Weekly | 1.00 |
Total Full Time Average Weekly Learner Contact Time 1.00 Hours
Required & Recommended Book List
Required Reading
2020-12-04 Basic and Clinical Pharmacology 15e McGraw-Hill Education / Medical
ISBN 126045231X ISBN-13 9781260452310
2020-12-04 Basic and Clinical Pharmacology 15e McGraw-Hill Education / Medical
ISBN 126045231X ISBN-13 9781260452310
Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Master key pharmacological concepts and practices with the most comprehensive, authoritative guide available Presented in full-color and packed with hundreds of illustrations, Basic and Clinical Pharmacology is the wide-ranging, engaging guide students have counted on for decades. Organized to reflect the course sequence in many pharmacology courses and in integrated curricula, the guide covers the important concepts students need to know about the science of pharmacology and its application to clinical practice. This edition has been extensively updated to provide expanded coverage of transporters, pharmacogenomics, and new drugs Delivers the knowledge and insight needed to excel in every facet of pharmacology!. Encompasses all aspects of medical pharmacology, including botanicals and over-the-counter drugs Major revisions of the chapters on immunopharmacology, antiseizure, antipsychotic, antidepressant, antidiabetic, anti-inflammatory, and antiviral drugs, prostaglandins, and central nervous system neurotransmitters New chapter on the increasingly relevant topic of cannabis pharmacology Each chapter opens with a case study, covers drug groups and prototypes, and closes with summary tables and diagrams that encapsulate important information Revised full-color illustrations provide more information about drug mechanisms and effects and help clarify important concepts Trade Name/Generic Name tables are provided at end of each chapter for easy reference when writing a chart order or prescription Includes descriptions of important new drugs released through May 2019 New and updated coverage of general concepts relating to recently discovered receptors, receptor mechanisms, and drug transporters
Required Reading
2012-11-28 Pharmacology for Pharmacy Technicians Mosby
ISBN 0323084974 ISBN-13 9780323084970
2012-11-28 Pharmacology for Pharmacy Technicians Mosby
ISBN 0323084974 ISBN-13 9780323084970
Organized to provide an in-depth review of the ASHP content requirements for pharmacology and anatomy and physiology, Pharmacology for Pharmacy Technicians, 2nd Edition is comprehensive, yet approachable. It offers complete coverage of body systems structure to correspond to the way pharmacology is taught in most programs, as well as patient scenarios, anatomy and physiology refreshers, drug monographs with pill photos, and a number of learning aids. Overviews of anatomy and physiology at the beginning of each body system unit provide a basic understanding of anatomy and physiology to help you understand how drugs work in the body. Mini drug monographs in every body system and drug classification chapter contain valuable drug information and pill photos for quick reference. Summary drug tables with generic/brand name, usual dose and dosing schedule, and warning labels offer at-a-glance access to information about specific drugs. Helpful Tech Notes enhance your understanding of the practical knowledge needed in the pharmacy setting and help you relate new concepts to practical use. Tech Alerts offer critical reminders and warnings to help you learn to identify and avoid common pharmacy errors. Technician's Corner critical thinking exercises prepare you for on-the-job situations by providing a set of facts and asking you to reach a conclusion. Updated drug information ensures you are familiar with the latest drug approvals and therapeutic considerations. Additional learning resources on the companion Evolve website include: Certification practice exam to better prepare you for the PTCB or ExCPT exam. More recall exercises and games to help you retain complex information.
Required Reading
2013-12-02 Clinical Toxicology, an Issue of Emergency Medicine Clinics of North America Elsevier
ISBN 0323266541 ISBN-13 9780323266543
2013-12-02 Clinical Toxicology, an Issue of Emergency Medicine Clinics of North America Elsevier
ISBN 0323266541 ISBN-13 9780323266543
This issue of Emergency Medicine Clinics focuses on Clinical Toxicology and is edited by Drs. Daniel Lugassy and Silas Smith and includes such topics as Emerging Drugs of Abuse, Pediatric Toxicology; Dosing and Medical Errors and Child Abuse,The Approach to Toxin-Induced Coagulopathy,The Approach to Toxin-Induced Cardiovascular Failure, The Approach to Toxin-Induced Metabolic Acidosis, The Approach to Withdrawal Syndromes, The Approach to Radiation Exposure, and more.
Module Resources
Non ISBN Literary Resources
Journal Resources
https://www.clintox.org/resources/clinical-toxicology
American Academy of Clinical Toxicology
https://www.springer.com/journal/228
European Journal of Clinical Pharmacology
URL Resources
Other Resources
Additional Information