NUTR08003 2019 Molecular Nutrition

This module explores the molecular and genetic basis of nutrients in health and disease and aims to equip students with the fundamentals of molecular biology and how this is applied to current research and understanding in nutrition. Key cellular processes and the genome wide influences of diet and nutrition will be addressed. The common laboratory methods used in the studying the effects of nutrients on the genome will also be explored.

Covering advanced nutrition with a comprehensive, easy-to-understand approach, Biochemical, Physiological, and Molecular Aspects of Human Nutrition, 3rd Edition focuses on the biology of human nutrition at the molecular, cellular, tissue, and whole-body levels. It addresses nutrients by classification, and describes macronutrient function from digestion to metabolism. This edition includes the new MyPlate dietary guide and recommendations from the Dietary Guidelines for Americans 2010, plus coverage of the historical evolution of nutrition and information on a wide range of vitamins, minerals, and other food components. In Biochemical, Physiological, and Molecular Aspects of Human Nutrition, lead authors Martha H. Stipanuk and Marie A. Caudill are joined by a team of nutrition experts in providing clear, concise, coverage of advanced nutrition.

• 55 expert contributors provide the latest information on all areas of the nutrition sciences.
• Nutrition Insight boxes discuss hot topics and take a closer look at basic science and everyday nutrition.
• Clinical Correlation boxes show the connection between nutrition-related problems and their effects on normal metabolism.
• Food Sources boxes summarize and simplify data from the USDA National Nutrient Database on the amount and types of foods needed to reach the recommended daily allowances for vitamins and minerals.
• DRIs Across the Life Cycle boxes highlight the latest data from the Institute of Medicine on dietary reference intakes for vitamins and minerals, including coverage of infants, children, adult males and females, and pregnant and lactating women.
• Life Cycle Considerations boxes highlight nutritional processes or concepts applicable to individuals of various ages and in various stages of the life span.
• Thinking Critically sections within boxes and at the end of chapters help in applying scientific knowledge to "real-life" situations.
• Lists of common abbreviations provide an overview of each chapter's content at a glance.
• Comprehensive cross-referencing by chapters and illustrations is used throughout.
• Current references and recommended readings connect you to nutrition-related literature and provide additional tools for research.

• Coverage of the USDA's MyPlate dietary guide reflects today's new approach to diet and nutrition.
• Recommendations outlined in the Dietary Guidelines for Americans 2010 are incorporated throughout the book.

• Updated format features more subheadings, tables, and bullets, making it easier to learn and recall key points.
• Updates of key chapters and boxes reflect significant changes within the fields of nutrition, biology, molecular biology, and chemistry.

• NEW illustrations simplify complex biochemical, physiological, and molecular processes and concepts.

The fascinating area of Nutrigenomics describes this daily communication between diet, food and nutrients, their metabolites and our genome. This book describes how nutrition shapes human evolution and demonstrates its consequences for our susceptibility to diseases, such as diabetes and atherosclerosis. Inappropriate diet can yield stress for our cells, tissues and organs and then it is often associated with low-grade chronic inflammation. Overnutrition paired with physical inactivity leads to overweight and obesity and results in increased burden for a body that originally was adapted for a life in the savannas of East Africa. Therefore, this textbook does not discuss a theoretical topic in science, but it talks about real life, and our life-long chat with diet. We are all food consumers, thus each of us is concerned by the topic of this book and should be aware of its mechanisms. The purpose of this book is to provide an overview on the principles of nutrigenomics and their relation to health or disease. We are not aiming to compete with more comprehensive textbooks on molecular nutrition, evolutionary biology, genomics, gene regulation or metabolic diseases, but rather will focus on the essentials and will combine, in a compact form, elements from different disciplines. In order to facilitate the latter, we favor a high figure-to-text ratio following the rule a picture tells more than thousand words. The content of this book is based on the lecture course Nutrigenomics, which is held since 2003 once per year by Prof. Carlberg at the University of Eastern Finland in Kuopio. The book is subdivided into three sections and twelve chapters. Following the "Introduction" there are sections on the "Molecular genetic basis" and the "Links to disease", which take a view on nutrigenomics from the perspective of molecular mechanisms or from the causes of metabolic diseases, respectively. Besides its value as a textbook, Nutrigenomics will be a usefull reference for individuals working in biomedicine.

Functional foods and nutraceuticals have received considerable interest in the past decade, largely due to increasing consumer awareness of the health benefits associated with food. Diet in human health is no longer a matter of simple nutrition: consumers are more proactive and increasingly interested in the health benefits of functional foods and their role in the prevention of illness and chronic conditions. This, combined with an aging population that focuses not only on longevity but also quality of life, has created a market for functional foods and nutraceuticals. A fully updated and revised second edition, "Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods" reflects the recent upsurge in "omics" technologies and features 48 chapters that cover topics including genomics, proteomics, metabolomics, epigenetics, peptidomics, nutrigenomics and human health, transcriptomics, nutri-ethics, and nanotechnology. This cutting-edge volume, written by a panel of experts from around the globe, reviews the latest developments in the field with an emphasis on the application of these novel technologies to functional foods and nutraceuticals. About the editorsDebasis Bagchi, Ph.D., MACN, CNS, MAIChEUniversity of Houston College of Pharmacy, Houston, TX, USA Anand Swaroop, Ph.D.Cepham Inc., Piscataway, NJ, USA Manashi Bagchi, Ph.D., FACNCepham Inc., Piscataway, NJ, USA Also available from Wiley "Bio-Nanotechnology: A Revolution in Food, Biomedical and Health Sciences"Edited by Debasis Bagchi, Manashi Bagchi, Hiroyoshi Moriyama, Fereidoon ShahidiISBN: 978-0-470-67037-8 "Antioxidants and Functional Components in Aquatic Foods"Edited by Hordur G. KristinssonISBN: 978-0-8138-1367-7 "Nanotechnology and Functional Foods: Effective Delivery of Bioactive Ingredients"Edited by Cristina Sabliov, Hongda Chen, Rickey YadaISBN: 978-1-118-46220-1

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