CHEM08004 2019 ADVANCED ORGANIC CHEMISTRY
Full Title
ADVANCED ORGANIC CHEMISTRY
Transcript Title
ADVANCED ORGANIC CHEMISTRY
Code
CHEM08004
Attendance
N/A %
Subject Area
CHEM - Chemistry
Department
LIFE - Life Sciences
Level
08 - NFQ Level 8
Credit
05 - 05 Credits
Duration
Semester
Fee
€
Start Term
2019 - Full Academic Year 2019-20
End Term
9999 - The End of Time
Author(s)
Declan Shelly
Programme Membership
SG_SPHAR_H08 201900 Bachelor of Science (Honours) in Pharmaceutical Science with Drug Development
SG_SPHAR_K08 201900 Bachelor of Science (Honours) in Pharmaceutical Science (Add-on)
Description
This module covers aromatic chemistry topics, including the reactivity of benzene derivatives and a range of heterocyclic compounds. The importance of stereochemistry in a pharmaceutical environment is also examined, including such topics as stereoselectivity, stereospecificity and asymmetric synthesis. Molecular orbital theory leading to product determination in cycloaddition and electrocyclic reactions are also studied.
Learning Outcomes
On completion of this module the learner will/should be able to;
1.
Evaluate the reactivity of a range of benzene derivatives.
2.
Identify and appraise a range of heterocyclic compounds.
3.
Describe stereoselectivity and stereospecificity.
4.
Explain the basis of nucleoplilic and electrophilic substitution reactions.
5.
Determine synthetic routes to a range of organic chemical compounds.
6.
Use molecular orbital theory to explain the products obtained in some cycloaddition and electrocyclic reactions.
Teaching and Learning Strategies
This module will be delivered full‑time. It will include lectures and class discussions.This approach is expected to address student learning needs. Moodle will be used as a repository of educational resources.
Module Assessment Strategies
Students will be assessed using a blend of essay / short answer questions, reinforced with a final written exam.
Repeat Assessments
Students may repeat Continuous Assessment and / or Final Theory Exam as required
Module Dependencies
Prerequisites
Organic Chemistry, Pharmaceutical Chemistry or equivalent.
Co-requisites
None
Incompatibles
None
Indicative Syllabus
Identify the factors influencing the reactivity and orientation of electrophilic substitution of benzene derivatives.
Evaluate products and reaction mechanisms involved in nucleophilic substitution reactions.
Develop synthetic pathways to prepare specific organic compounds.
Examine the importance of heterocyclic compounds in pharmaceutical synthesis.
Describe the importance of stereochemistry in the synthesis of pharmaceutical compounds.
Use molecular orbital theory to determine the structure of products obtained (both thermally and photochemically) from a range of cycloaddition and electrocyclic reactions.
Coursework & Assessment Breakdown
Coursework & Continuous Assessment
40 %
End of Semester / Year Formal Exam
60 %
Coursework Assessment
| Title | Type | Form | Percent | Week | Learning Outcomes Assessed | |
|---|---|---|---|---|---|---|
| 1 | Class discussions. | Formative | Performance Evaluation | - % | OnGoing | 1,2,3,4,5,6 |
| 2 | Essay | Coursework Assessment | Essay | 20 % | Week 6 | |
| 3 | Short answer questions. | Coursework Assessment | Closed Book Exam | 20 % | Week 12 | 1,2,3,4,5,6 |
End of Semester / Year Assessment
| Title | Type | Form | Percent | Week | Learning Outcomes Assessed | |
|---|---|---|---|---|---|---|
| 1 | Written Examination. | Final Exam | UNKNOWN | 60 % | End of Term | 1,2,3,4,5,6 |
Full Time Mode Workload
| Type | Location | Description | Hours | Frequency | Avg Workload |
|---|---|---|---|---|---|
| Lecture | Tiered Classroom | Lecture | 3 | Weekly | 3.00 |
| Independent Learning | UNKNOWN | Self Study | 4 | Weekly | 4.00 |
Total Full Time Average Weekly Learner Contact Time 3.00 Hours
Required & Recommended Book List
Required Reading
2015-02-27 Organic Chemistry Cengage Learning
ISBN 9781305686465 ISBN-13 1305686462
2015-02-27 Organic Chemistry Cengage Learning
ISBN 9781305686465 ISBN-13 1305686462
The most trusted and best-selling text for organic chemistry just got better! Updated with more coverage of nuclear magnetic resonance spectroscopy, expanded with new end-of-chapter mechanism problems and Practice Your Scientific Reasoning and Analysis questions, and enhanced with OWLv2, the latest version of the leading online homework and learning system for chemistry, John McMurry's ORGANIC CHEMISTRY continues to set the standard for the course. The Ninth Edition also retains McMurry's hallmark qualities: comprehensive, authoritative, and clear. McMurry has developed a reputation for crafting precise and accessible texts that speak to the needs of instructors and students. More than a million students worldwide from a full range of universities have mastered organic chemistry through his trademark style, while instructors at hundreds of colleges and universities have praised his approach time and time again. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.
Required Reading
1998-06-01 Organic Chemistry
ISBN 0138924643 ISBN-13 9780138924645
1998-06-01 Organic Chemistry
ISBN 0138924643 ISBN-13 9780138924645
Module Resources
Non ISBN Literary Resources
None
Journal Resources
None
Other Resources
Module Lecture Notes.
Additional Information
None