CHEM07002 2019 Pharmaceutical Chemistry

Name, identify and recognise the structure of a range of selected organic groups of molecules that are relevant to the pharmaceutical and chemical industry, including their structure, stereochemistry and synthesis.

Demonstrate knowledge of interfacial chemistry at the liquid / gas / solid boundaries.  

Relate the concepts of interfacial chemistry and the functions of the organic groups covered in the module to their role in pharmaceutical and chemistry related applications.

Demonstrate numerical and problem solving skills to examine properties and illustrate examples relevant to the content of the module.  

This module will be delivered Full time. It will include lectures augmented by independent learning and directed learning.  Moodle will be use as repository of education resources and as a means of assessment e.g. uploading assignments.

This module is 40% continuous assessment and 60% final exam.  Students will be assessed using a blend of essay / short answer questions, reinforced with a final written examination.

Repeat Continuous Assessment and/or Final Exam.

Stereochemistry - optical activity, specific rotation, chirality, enantiomerism, configuration of stereoisomers; rules for the specification of R & S configuration of optically active compounds; racemic modifications and distereoisomers.

Recognise the structure and understand the nomenclature of a variety of organic molecules such as simple carbohydrates, Terpenes, Lipids, Fats, Fatty Acids and steroids.

Interfacial phenomena, surface tension, spreading coefficients, Youngs equation, capillary action, Laplace equation and curved surfaces.

Definition and classification of surface active agents (soluble and insoluble), surface excess concentration, LB instrument and curves.

Gas / Solid Adsorption characteristics, isotherms, Langmuir behaviour.  Fundamental chemical properties pH, pKa, Log P and partition coefficients.

The application of all of the above to pharmaceutical and chemical industry.