BIOC06008 2019 Biochemistry 1

Explain the function of macromolecules in the cell.

Describe mammalian cellular energetics.

Describe the action of enzymes and discuss factors that affect enzyme kinetics.

Outline the organisation of nucleic acids in the cell.

Illustrate the cell cycle.

Relate some applications of molecular biology.  

Perform and report on, biochemical laboratory experiments and communicate information accurately and effectively using written, visual and numeral forms.

The Biochemistry One module will be delivered full time and will include lectures, laboratory practicals and tutorials.  Moodle will be used as a repository of educational resources and as a means of assessment where appropriate.

The Biochemistry One module is 50% Practical and 50% Theory.  

Laboratory skills and report-writing ability are assessed as part of the practical work performed during the module (50%).  There will be two MCQs (15%) and there will be a Final Exam (35%)

The student must reach an assigned gate of 30% in the final exam and achieve 40% overall to pass the subject. 

Repeat Continuous Assessment and/or Final Exam

Biomembranes

Amino acids, protein folding, protein sequencing and protein purification/isolation. 

Enzymology

The structure and function of proteins.  Enzyme kinetics

Mammalian Cellular Energetics

Glycolysis, Krebs Cycle ,Oxidative Phosphorylation and fermentation.

The Organisation of Nucleic acids in the cell

DNA structure, histones, nucleosomes, 

Cell Cycle & Cell growth control

Cell cycle control in mammalian cells, checkpoints in cell cycle regulation, onset of cancer.

Laboratory Practicals and Student Centred Learning

The module will include laboratory practicals which will supplement the lecture based learning.