General Details

Full Title
Transcript Title
N/A %
Subject Area
BIOC - Biochemistry
LIFE - Life Sciences
06 - NFQ Level 6
05 - 05 Credits
Start Term
2020 - Full Academic Year 2020-21
End Term
9999 - The End of Time
Margaret Doherty
Programme Membership
SG_SAPMS_H08 202000 Bachelor of Science (Honours) in Applied Medical Sciences SG_SBIOM_H08 202000 Bachelor of Science (Honours) in Biomedical and BioIndustrial Sciences


To explain core functions, structures, of the major biological macromolecules of the cell and how they integrate into cellular function. This module is designed to provide fundamental understanding of the chemical processes which underlie the biochemical reactions responsible for life and is essential for further study of the biosciences. The concepts introduced in this module will be further developed in later modules of study. 


Learning Outcomes

On completion of this module the learner will/should be able to;


Describe the structure, function of biological macromolecules in the cell


Describe mammalian cellular energetics, and discuss factor that affect enzyme kinetics


Outline the organisation of nucleic acids in the cell


Explain the role of the cell cycle and cell signalling.

Teaching and Learning Strategies

This module is taught by lectures supported by self-directed reading material, voice-supported presentations, and a variety of applied formative assessments. A range of Computer-Aided Learning (CAL) packages are also used to support this module. Students are provided with electronic materials for self-assessment and preparation for examinations. Self-directed, student-centred, independent learning is also encouraged through completion of module coursework.

Module Assessment Strategies

Continuous Assessment and Final Examination

Repeat Assessments

As per IT Sligo procedures

Indicative Syllabus

The module will cover a wide range of core aspects of biochemistry and set this in a clinical and industrial context, including:

Biomembranes Lipid structure and function and organisation into membranes. Membrane proteins. Cell isolation & subcellular fractionation.

Transport across membranes ATP powered pumps, ion channels, action potentials and neurotransmitter release in neurons

Proteins & Enzymes The structure & function of proteins. Enzyme kinetics

Mammalian Cellular Energetics Carbohydrate structure and metabolism, Glycolysis, Krebs Cycle & Oxidative Phosphorylation.

The Organisation of Nucleic acids in the cell DNA & RNA structure, histones, nucleosomes, supercoiling

Cell Cycle & Cell growth control Cell cycle control in mammalian cells, checkpoints in cell cycle regulation, onset of cancer.

Coursework & Assessment Breakdown

Coursework & Continuous Assessment
40 %
End of Semester / Year Formal Exam
60 %

Coursework Assessment

Title Type Form Percent Week Learning Outcomes Assessed
1 Coursework Coursework Assessment Multiple Choice/Short Answer Test 40 % OnGoing 1,2,3,4

End of Semester / Year Assessment

Title Type Form Percent Week Learning Outcomes Assessed
1 End Exam Final Exam Assessment 60 % End of Semester 1,2,3,4

Online Learning Mode Workload

Type Location Description Hours Frequency Avg Workload
Online Lecture Not Specified Lecture 1 Weekly 1.00
Independent Learning Not Specified Independent Learning 6 Weekly 6.00
Total Online Learning Average Weekly Learner Contact Time 1.00 Hours

Required & Recommended Book List

Required Reading
2019-03-12 Biochemistry WH Freeman
ISBN 1319114652 ISBN-13 9781319114657

For four decades, this extraordinary textbook played a pivotal role in the way biochemistry is taught, offering exceptionally clear writing, and innovative graphics, coverage of the latest research techniques and advances, and a signature emphasis on physiological and medical relevance. Those defining features are at the heart of this new edition. Paired for the first time with SaplingPlus the most innovative digital solution for Biochemistry students. Offering the best combination of resources to help students visualise material and develop successful problem-solving skills in an effort to help students master complex concepts in isolation, and draw on that mastery to make connections across concepts.

Required Reading
2016-11-01 Principles of Biochemistry 7e
ISBN 1464126119 ISBN-13 9781464126116
Required Reading
2016-06-03 Molecular Cell Biology W. H. Freeman
ISBN 1464187444 ISBN-13 9781464187445
Required Reading
2016-12-01 Cell Biology Elsevier
ISBN 0323341268 ISBN-13 9780323341264

The much-anticipated 3rd edition of "Cell Biology" delivers comprehensive, clearly written, and richly illustrated content to today's students, all in a user-friendly format. Relevant to both research and clinical practice, this rich resource covers key principles of cellular function and uses them to explain how molecular defects lead to cellular dysfunction and cause human disease. Concise text and visually amazing graphics simplify complex information and help readers make the most of their study time.

Module Resources

Non ISBN Literary Resources



URL Resources

Students will also be directed to online resources as required, including relevant up-to-date scientific literature, and to other relevant reading material during teaching sessions and via the online module materials.

Other Resources


Additional Information