BIOC06007 2020 Biochemistry
To explain the core functions, structures, of the major biological macromolecules of the cell and how they integrate into cellular function. This module is designed to provide fundamental understanding of the chemical processes which underlie the biochemical reactions responsible for life and is essential for further study of the biosciences. The concepts introduced in this module will be further developed in later modules of study.
Learning Outcomes
On completion of this module the learner will/should be able to;
Describe the structure, function of biological macromolecules in the cell
Describe mammalian cellular energetics, and discuss factor that affect enzyme kinetics
Outline the organisation of nucleic acids in the cell
Explain the role of the cell cycle and cell signalling.
Teaching and Learning Strategies
This module is taught by lectures supported by self-directed reading material, voice-supported presentations, and a variety of applied formative assessments. A range of Computer-Aided Learning (CAL) packages are also used to support this module. Students are provided with electronic materials for self-assessment and preparation for examinations. Self-directed, student-centred, independent learning is also encouraged through completion of module coursework.
Module Assessment Strategies
Continuous Assessment and Final Examination
Repeat Assessments
As per IT Sligo procedures
Indicative Syllabus
The module will cover a wide range of core aspects of biochemistry and set this in a clinical and industrial context, including:
Biomembranes Lipid structure and function and organisation into membranes. Membrane proteins. Cell isolation & subcellular fractionation.
Transport across membranes ATP powered pumps, ion channels, action potentials and neurotransmitter release in neurons
Proteins & Enzymes The structure & function of proteins. Enzyme kinetics
Mammalian Cellular Energetics Carbohydrate structure and metabolism, Glycolysis, Krebs Cycle & Oxidative Phosphorylation.
The Organisation of Nucleic acids in the cell DNA & RNA structure, histones, nucleosomes, supercoiling
Cell Cycle & Cell growth control Cell cycle control in mammalian cells, checkpoints in cell cycle regulation, onset of cancer.
Coursework & Assessment Breakdown
Coursework Assessment
Title | Type | Form | Percent | Week | Learning Outcomes Assessed | |
---|---|---|---|---|---|---|
1 | Coursework | Coursework Assessment | Multiple Choice/Short Answer Test | 40 % | OnGoing | 1,2,3,4 |
End of Semester / Year Assessment
Title | Type | Form | Percent | Week | Learning Outcomes Assessed | |
---|---|---|---|---|---|---|
1 | End Exam | Final Exam | Assessment | 60 % | End of Semester | 1,2,3,4 |
Online Learning Mode Workload
Type | Location | Description | Hours | Frequency | Avg Workload |
---|---|---|---|---|---|
Online Lecture | Not Specified | Lecture | 1 | Weekly | 1.00 |
Independent Learning | Not Specified | Independent Learning | 6 | Weekly | 6.00 |
Required & Recommended Book List
2019-03-12 Biochemistry WH Freeman
ISBN 1319114652 ISBN-13 9781319114657
For four decades, this extraordinary textbook played a pivotal role in the way biochemistry is taught, offering exceptionally clear writing, and innovative graphics, coverage of the latest research techniques and advances, and a signature emphasis on physiological and medical relevance. Those defining features are at the heart of this new edition. Paired for the first time with SaplingPlus the most innovative digital solution for Biochemistry students. Offering the best combination of resources to help students visualise material and develop successful problem-solving skills in an effort to help students master complex concepts in isolation, and draw on that mastery to make connections across concepts.
2016-11-01 Principles of Biochemistry 7e
ISBN 1464126119 ISBN-13 9781464126116
2016-06-03 Molecular Cell Biology W. H. Freeman
ISBN 1464187444 ISBN-13 9781464187445
2016-12-01 Cell Biology Elsevier
ISBN 0323341268 ISBN-13 9780323341264
The much-anticipated 3rd edition of "Cell Biology" delivers comprehensive, clearly written, and richly illustrated content to today's students, all in a user-friendly format. Relevant to both research and clinical practice, this rich resource covers key principles of cellular function and uses them to explain how molecular defects lead to cellular dysfunction and cause human disease. Concise text and visually amazing graphics simplify complex information and help readers make the most of their study time.
Module Resources
Students will also be directed to online resources as required, including relevant up-to-date scientific literature, and to other relevant reading material during teaching sessions and via the online module materials.
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