BIO09046 2019 Upstream Bioprocessing Practical
This module covers much of the practical skills associated with cell culture and upstream processing in biopharmaceutical operations. The relevant learning is acquired through the completion of laboratory-based and pilot-plant based practical sessions that are designed to impart the required knowledge and skills required for upstream processing operations.
Learning Outcomes
On completion of this module the learner will/should be able to;
Demonstrate a range of practical skills associated with upstream processing in the biopharmaceutical industry.
Interpret and evaluate the data and results obtained from various upstream processing practicals.
Demonstrate the skills required for upstream bioprocessing operations.
Demonstrate effective communication skills.
Teaching and Learning Strategies
The range of practical sessions in NIBRT will cover some or all of the following:
- Aseptic technique
- Cell culture techniques including cell counting (manual and automated), cell sampling and metabolite analysis
- Bioreactor set-up for SIP
- Disposable Bioreactor set-up
- Centrifuge set-up and operation
Module Assessment Strategies
As this is a practical based module, attendance at the NIBRT practical sessions is a requirement. Some of the module assessment will take place during the practical sessions.
The assessment approach for this module is 100% continuous assessment, with a range of assessment methods employed including short-form assessment exams and practical report write-ups.
Repeat Assessments
as per Q manual
Module Dependencies
Indicative Syllabus
The range of practical sessions in NIBRT will cover some or all of the following:
- Aseptic technique
- Cell culture techniques including cell counting (manual and automated), cell sampling and metabolite analysis
- Bioreactor set-up for SIP
- Disposable Bioreactor set-up
- Centrifuge set-up and operation
Coursework & Assessment Breakdown
Coursework Assessment
Title | Type | Form | Percent | Week | Learning Outcomes Assessed | |
---|---|---|---|---|---|---|
1 | Closed Book Exam End of practical assessment exams. | Coursework Assessment | Closed Book Exam | 25 % | Any | 1,2,3 |
2 | pre practical assessment | Coursework Assessment | Assessment | 25 % | Any | 1,2 |
3 | Individual Project Research project report and presentation. | Coursework Assessment | Written Report/Essay | 50 % | End of Semester | 2,3,4 |
Part Time Mode Workload
Type | Location | Description | Hours | Frequency | Avg Workload |
---|---|---|---|---|---|
Lecture | Not Specified | Ongoing lectures. | 1 | Fortnightly | 0.50 |
Independent Learning | UNKNOWN | Research project report and presentation. | 3 | Weekly | 3.00 |
Practical / Laboratory | Science Laboratory | NIBRT Training Facility attendance. | 16 | UNKNOWN | 16.00 |
Module Resources
Doran, Pauline M. 'Bioprocess Engineering Principles'. Academic Press. 1995.
Ratledge, Colin and Kristiansen Bjorn. 'Basic Biotechnology'. Cambridge Press. 2001.
Walsh, Gary. 'Biopharmaceuticals'. Wiley. 2003.
as above
as above
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