BIO08037 2019 BIOPHARMACEUTICAL SCIENCE PRACTICAL
Full Title
BIOPHARMACEUTICAL SCIENCE PRACTICAL
Transcript Title
BIOPHARMACEUTICAL SCIENCE PRAC
Code
BIO08037
Attendance
N/A %
Subject Area
BIO - Bio Tech/Eng/Chem
Department
LIFE - Life Sciences
Level
08 - NFQ Level 8
Credit
10 - 10 Credits
Duration
Semester
Fee
€
Start Term
2019 - Full Academic Year 2019-20
End Term
9999 - The End of Time
Author(s)
Kieran Tobin, Mary Butler
Programme Membership
SG_SBIOP_E08 201900 Level 8 Certificate in Science in Biopharmaceutical Science
SG_SBIOT_E08 201900 Certificate in Science in Bioprocessing Technologies SG_SBIOT_E08
SG_SBIOP_K08 201900 Bachelor of Science (Honours) in Biopharmaceutical Science.
SG_SCOLI_E08 201900 Certificate in Science in Colin McLeans Test Programme
SG_SBIOT_E08 202200 Certificate in Bioprocessing Technologies SG_SBIOT_E08
SG_SBIOP_K08 202200 Bachelor of Science (Honours) in Biopharmaceutical Science (Add-on)
Description
This Biopharma laboratory practical module will provide students with practical knowledge, know-how and practical skills associated with biopharmaceutical operations. The relevant learning is achieved through the completion of a sequence of laboratory-based and pilot-plant based practicals and experiments that are designed to impart the required expertise. There will also be some research project work associated with the laboratory practicals.
Learning Outcomes
On completion of this module the learner will/should be able to;
1.
Demonstrate a range of practical knowledge and skills associated with upstream bioprocessing operations
2.
Demonstrate a range of practical knowledge and skills associated downstream bioprocessing operations.
3.
Demonstrate a range of practical knowledge and skills associated with aseptic processing and filling operations
4.
Perform project work related to the practical sessions
5.
Evaluate the data and results obtained from the practical sessions
6.
Demonstrate effective communication skills in a written format.
Teaching and Learning Strategies
as above
Module Assessment Strategies
The assessment strategy will comprise of both observation of skills being acquired as well as formal assessment of knowledge acquisition. There will be a project research element associated with the assessment strategy also.
The miniproject is a MANDATORY form of assessment for any modules on this programme with a miniproject component.
Repeat Assessments
.
Indicative Syllabus
The range of lab-based and pilot plant-based practical sessions may include some or all of the following:
- Facility Tour - overview of all aspects of the bioprocess – upstream, harvest, downstream and fill finish, along with associated services such as buffer prep, media prep, and clean utilities that service the plant.
- Cell Culture Processing - aseptic technique, cell culturing, cell sampling, counting and substrate analysis.
- Downstream Processing - protein concentration using ultrafiltration and buffer exchange using diafiltration.
- Aseptic Procssing - contamination control, filling line operation and glove integrity testing.
Coursework & Assessment Breakdown
Coursework & Continuous Assessment
100 %
Coursework Assessment
| Title | Type | Form | Percent | Week | Learning Outcomes Assessed | |
|---|---|---|---|---|---|---|
| 1 | Closed Book Exam Exam at end of day 3 of lab. practicals. | Coursework Assessment | Closed Book Exam | 40 % | Week 7 | 1,2,3 |
| 2 | Project Research project based around the lab. practicals. | Coursework Assessment | Project | 60 % | Week 10 | 4,5,6 |
Part Time Mode Workload
| Type | Location | Description | Hours | Frequency | Avg Workload |
|---|---|---|---|---|---|
| Practical / Laboratory | Science Laboratory | Attendance at laboratory practicals. | 22 | Once Per Semester | 1.47 |
| Independent Learning | UNKNOWN | Research project based on lab. practicals. | 3 | Weekly | 3.00 |
Total Part Time Average Weekly Learner Contact Time 1.47 Hours
Module Resources
Non ISBN Literary Resources
Walsh, Gary. 'Pharmaceutical Biotechnology'. Wiley. 2007.:-:-#160:::::-:-#160::::
Ratledge, Colin and Kristiansen Bjorn. 'Basic Biotechnology'. Cambridge Press. 2001.
Doran, Pauline M. 'Bioprocess Engineering Principles'. Academic Press. 1995.
Hatti-Kaul, Rajni and Mattiasson, Bo. 'Isolation and Purification of Proteins'. Marcel-Dekker. 2003.:-:-#160::::
Journal Resources
as per moodle page
URL Resources
as per moodle page
Other Resources
None
Additional Information
None