BIO07027 2019 BIOPROCESS ENGINEERING THEORY
Full Title
BIOPROCESS ENGINEERING THEORY
Transcript Title
BIOPROCESS ENGINEERING THEORY
Code
BIO07027
Attendance
N/A %
Subject Area
BIO - Bio Tech/Eng/Chem
Department
LIFE - Life Sciences
Level
07 - NFQ Level 7
Credit
05 - 05 Credits
Duration
Stage
Fee
€
Start Term
2019 - Full Academic Year 2019-20
End Term
9999 - The End of Time
Author(s)
Paul Walsh
Programme Membership
SG_SBIOP_J07 201900 Bachelor of Science in Biopharmaceutical Science (Add-on)
SG_SBIOE_E07 201900 Certificate in Bioprocess Engineering
Description
This module aims to provide the student with a fundamental understanding of the key elements of bioprocess engineering control systems and the key role they play in the processing of modern biopharmaceutical products.
Learning Outcomes
On completion of this module the learner will/should be able to;
1.
Explain the business case and overall critical importance for the design of process control systems in bioprocessing.
2.
Outline the main control system components including process controllers, actuators, feedback sensors etc.
3.
Explain the operation of a modern PLC system, how the inputs and outputs are connected to it and how a programme is executed from it.
4.
Discuss the principal monitoring and control systems in use for biopharmaceutical processes.
5.
Explain the role and operation of SCADA (supervisory control and data acquisition) systems for modern bioprocessing.
Teaching and Learning Strategies
N/A
Module Assessment Strategies
A variety of assessment strategies will be employed for this module including the following: online exams/quizzes, assignments, final written exam paper.
Repeat Assessments
N/A
Indicative Syllabus
Process control and monitoring is a critical feature of the modern biopharmaceutical operation becasuse of the strict regulatory requirements on product release. Its applications range from status monitoring of a simple system to continuous or batch process control and reporting of a complex bioreactor process. All of these topics are explored in this module which starts with an overview of a typical control system and its principla components. The programme material will include the some or all of the following topics:
- The business case and strategic perspective for using process monitoring and control.
- The design and implementation of control system components including process controllers, actuators, valves etc.
- The analysis of a variety of practical process control design strategies.
- The main bioprocess control loops with associated equipment and control technologies.
- The architecture, operation and programming of a typical PLC system.
- The application of PLC control theory for a typical bioreactor control system.
- SCADA systems, their design and application for bioprocessing control and monitoring.
Coursework & Assessment Breakdown
Coursework & Continuous Assessment
50 %
End of Semester / Year Formal Exam
50 %
Coursework Assessment
| Title | Type | Form | Percent | Week | Learning Outcomes Assessed | |
|---|---|---|---|---|---|---|
| 1 | Multiple Choice Questions | Coursework Assessment | Multiple Choice/Short Answer Test | 10 % | Week 5 | 1,2,3,4,5 |
| 2 | Multiple Choice Questions | Coursework Assessment | Multiple Choice/Short Answer Test | 20 % | Week 10 | 4,5 |
| 3 | SAQ | Coursework Assessment | Assessment | 20 % | Week 13 | 1,2,3,4,5 |
End of Semester / Year Assessment
| Title | Type | Form | Percent | Week | Learning Outcomes Assessed | |
|---|---|---|---|---|---|---|
| 1 | Final Exam | Final Exam | Closed Book Exam | 50 % | End of Term | 1,2,3,4,5 |
Part Time Mode Workload
| Type | Location | Description | Hours | Frequency | Avg Workload |
|---|---|---|---|---|---|
| Lecture | Not Specified | Online | 1 | Weekly | 1.00 |
| Directed Learning | Not Specified | Course Notes/Slides | 3 | Weekly | 3.00 |
| Independent Learning | UNKNOWN | Mini Research Assignment | 3 | Weekly | 3.00 |
Total Part Time Average Weekly Learner Contact Time 4.00 Hours
Module Resources
Non ISBN Literary Resources
Doran, P.M., Bioprocess Engineering Principles, Academic Press, 2006.
Journal Resources
N/A
URL Resources
N/A
Other Resources
http://www.cheric.org/educational/control (Introduction to process control; understand the measurements - DP cell; Understand the actuator - control valve; PID controller tuning using various methods; Open loose response in the time and frequency domains; Closed loop PID response and stability; Feedforward and cascade control.)
http://www.pc-education.mcmaster.ca/instrumentation/go_inst.htm (Sensors, instrumentation and control valves).
Additional Information
None