BIO07010 2019 Cell Culture Processing Level 7.

General Details

Full Title
Cell Culture Processing Level 7.
Transcript Title
Cell Culture Processing Level
N/A %
Subject Area
BIO - Bio Tech/Eng/Chem
LIFE - Life Sciences
07 - NFQ Level 7
10 - 10 Credits
Start Term
2019 - Full Academic Year 2019-20
End Term
9999 - The End of Time
Paul Walsh
Programme Membership
SG_SBIOP_J07 201900 Bachelor of Science in Biopharmaceutical Science (Add-on) SG_SBIOP_E07 201900 Certificate in Biopharmaceutical Processing

This module aims to provide students with a broad understanding of  the theory  of cell culture processing as it relates to the biosynthesis of modern biopharmaceutical products.  It will include a combination of theory and practical laboratory work.    

Learning Outcomes

On completion of this module the learner will/should be able to;


Outline the fundamentals of cell biology, cell culture processing and explain the process kinetics relating to cell growth.


Describe the various bioreactor designs available and their key features including relative advantages and disadvantages of different operating loops.


Describe the main operating cvontrol loops for a modern bioreactor and the critical control parameters associated with bioreactor performance.


Perform a range of laboratory and pilot plant practicals relating to cell culture processing.


Communicate scientific information and data in an appropriate format.

Teaching and Learning Strategies


Module Assessment Strategies

A combination of continuous assessment strategies, some laboratory experiments and an end-of-term exam.

Repeat Assessments


Indicative Syllabus

·         Overview of Cell Biology relating to Cell Culture Processing and Bioreactor Operations.

·         Practical cell counting techniques, cell density and cell viability measurements.

·         Kinetics of Cell Growth, Yield and Productivities.

·         Energy and Mass Transfer Systems for Bioprocessing. 

·         Bioreactor Design and Engineering. 

·         Practical Bioreactor Operation and Control of critical parameters.   


Coursework & Assessment Breakdown

Coursework & Continuous Assessment
50 %
End of Semester / Year Formal Exam
50 %

Coursework Assessment

Title Type Form Percent Week Learning Outcomes Assessed
1 Continuous Assessment Short-form exams and lab. practical write-ups. Coursework Assessment Assessment 10 % Week 7 1,2,3,4,5
2 Assessment Coursework Assessment Assessment 10 % Week 12
3 NIBRT Assessment Formative Assessment - % Week 7
4 NIBRT Practical Report Practical Assessment 20 % Week 9

End of Semester / Year Assessment

Title Type Form Percent Week Learning Outcomes Assessed
1 Final Exam Final Exam Closed Book Exam 50 % End of Term 1,2,3

Part Time Mode Workload

Type Location Description Hours Frequency Avg Workload
Lecture Distance Learning Suite Online lecture. 1 Weekly 1.00
Practical / Laboratory Science Laboratory Laboratory Practical Experiments. 16 Once Per Semester 1.07
Directed Learning Not Specified Directed self-study. 5 Weekly 5.00
Total Part Time Average Weekly Learner Contact Time 7.07 Hours

Module Resources

Non ISBN Literary Resources

 ‘Pharmaceutical Biotechnology - Concepts and Applications' by Gary Walsh.

Wiley Publications.  2007.  ISBN - 978-0-470-01244-4.


‘Basic Biotechnology' by Colin Ratledge and Bjorn Kristiansen.

Cambridge Press. 2001.  ISBN - 0-521-779170.


'Bioprocess Engineering - Basic Concepts' by  Shuler,M.L. and Kargi F.

Journal Resources


URL Resources


Other Resources


Additional Information