BIO06023 2019 Introduction to Biopharmaceuticals

General Details

Full Title
Introduction to Biopharmaceuticals
Transcript Title
Introduction to Biopharmaceuti
Code
BIO06023
Attendance
N/A %
Subject Area
BIO - Bio Tech/Eng/Chem
Department
LIFE - Life Sciences
Level
06 - Level 6
Credit
05 - 05 Credits
Duration
Semester
Fee
Start Term
2019 - Full Academic Year 2019-20
End Term
9999 - The End of Time
Author(s)
Margaret Doherty
Programme Membership
SG_SPHAR_B07 201900 Bachelor of Science in Pharmaceutical Science with Drug Development SG_SPHAR_H08 201900 Bachelor of Science (Honours) in Pharmaceutical Science with Drug Development SG_SPHAR_C06 202100 Higher Certificate in Science in Pharmaceutical Science
Description

Introduction to Biopharmaceuticals will provide the student with a broad overview of the Biopharmaceutical sector.

Learning Outcomes

On completion of this module the learner will/should be able to;

1.

Demonstrate knowledge of the various technologies and disciplines that contribute to Biotechnology and Biopharmaceutical drug target discovery. 

2.

Identify and describe the different types of Biopharmaceutical products including proteins, antibodies, hormones, nucleic acids etc. 

3.

Explain the fundamental techniques of genetic engineering and provide examples of their use in the production of bioproducts.

4.

Evaluate cell models for expression of exogenous gene products and explain the process of gene expression and regulation within these systems.

5.

Effectively communicate scientific knowledge in an appropriate format.

Teaching and Learning Strategies

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Module Assessment Strategies

Assessment of the Introduction to Biopharmaceuticals module will include both continuous assessment and a terminal exam.  Continuous assessment  will involve a range of assessment types including multiple choice quizzes, a small individual project and a series of classroom based assignments.  The multiple choice quizzes will assess subject knowledge while the small project will allow students to work independently to source, interpret and apply appropriate and referenced literature on a given topic. The classroom based assignments will include computer based practical's designed to employ advanced data analysing, synthesising and summarising skills in a scientific work setting. 

2 MCQs (Between weeks 5 and 10)

Small project (Week 9)

 

Repeat Assessments

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Indicative Syllabus

Introduction to the most commonly produced biopharmaceutical products and their methods of production.

  • Structure and function of proteins. 
  • Synthesis of proteins.
  • The role of immunology, antibody technologies.
  • The Endocrine System & Biohormones. 
  • Vaccines, Antisense technology & Biosimilars. 

Fundamental techniques of genetic engineering 

  • Cloning
  • PCR
  • Restriction enzymes
  • Vector systems

Expression Systems

  • Process of gene expression and regulation 
  • Cell line selection for optimal protein expression.  
  • Transformation & Transfection technologies

 

 

Coursework & Assessment Breakdown

Coursework & Continuous Assessment
60 %
End of Semester / Year Formal Exam
40 %

Coursework Assessment

Title Type Form Percent Week Learning Outcomes Assessed
1 Multiple Choice Coursework Assessment Multiple Choice/Short Answer Test 30 % OnGoing 1,2,3,4,5
2 Individual Project Coursework Assessment Assignment 20 % Week 9 3
3 Continuous Assessment Coursework Assessment Open Book Exam 10 % OnGoing 1,2,3,4,5

End of Semester / Year Assessment

Title Type Form Percent Week Learning Outcomes Assessed
1 Final Exam Final Exam Closed Book Exam 40 % End of Term 1,2,3,4,5
             
             

Full Time Mode Workload


Type Location Description Hours Frequency Avg Workload
Lecture Tiered Classroom Lecture 2 Weekly 2.00
Group Learning Flat Classroom Group Learning 1 Weekly 1.00
Independent Learning UNKNOWN Self Study 4 Weekly 4.00
Total Full Time Average Weekly Learner Contact Time 2.00 Hours

Required & Recommended Book List

Recommended Reading
2018 Current Developments in Biotechnology and Bioengineering: Synthetic Biology, Cell Engineering and Bioprocessing Technologies Elsevier

Recommended Reading
2018 Biochemistry and Molecular Biology Oxford

Recommended Reading
2014 Production of Recombinant Proteins: Novel Microbial and Eukaryotic Expression Systems Production of Recombinant Proteins: Novel Microbial and Eukaryotic Expression Systems Wiley-Vch

Required Reading
2005 Biopharmaceuticals: Biochemistry and Biotechnology Wiley

Module Resources

Non ISBN Literary Resources

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Journal Resources

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URL Resources

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Other Resources

None

Additional Information

None